Forskning og antibiotika styringsprogram – Antibiotika.no

Forskning og antibiotika styringsprogram

Antibiotika styringsprogram (ASP) er program med kvalitetsforbedringstiltak som har som mål å bedre forskrivning og bruk av antibiotika. Dvs. at rett medikament, i rett dose, rett administrasjonsform (i.v./ tablett) og rett lengde gis til den enkelte pasient, med færrest mulige bivirkninger, og med minst mulig resistensutvikling.

I mer enn to ti-år har det blitt publisert vitenskapelige artikler om ASP. Vi presenterer her publikasjoner som viser forskjellige aspekter av slike program. Emnene er listet alfabetisk og de nyeste artiklene presenteres først.

Vitenskapelig er utfordringen nå å identifisere tiltak innenfor ASP som kan gi varig endring av antibiotikaforbruket.

Eksempler på lokal tilpasning

Andersen et al. A managed multidisciplinary programme on multi-resistant Klebsiella pneumoniae in a Danish university hospital. BMJ qual Saf. 2013

Wertheim et al. Providing impetus, tools, and guidance to strengthen national capacity for antimicrobial stewardship in Viet Nam. PLoS Med. 2013

Schouten et al. Tailored interventions to improve antibiotic use for lower respiratory tract infections in hospitals: a cluster-randomized, controlled trial. Clin Infect Dis. 2007

Elektronikk

Zaidi et al. Using formative evaluation to improve uptake of a web-based tool to support antimicrobial stewardship. J Clin Pharm Ther. 2013.

Charani et al. An analysis of the development and implementation of a smartphone application for the delivery of antimicrobial prescribing policy: lessons learnt. J Antimicrob Chemother. 2012

Buising et al. Electronic antibiotic stewardship–reduced consumption of broad-spectrum antibiotics using a computerized antimicrobial approval system in a hospital setting. J Antimicrob Chemother. 2008.

Etablering

Ashiru-Oredope et al. Improving the quality of antibiotic prescribing in the NHS by developing a new Antimicrobial Stewardship Programme: Start Smart–Then Focus. J Antimicrob Chemother, 2012.

Nathwani et al. Scottish Antimicrobial Prescribing Group (SAPG): development and impact of the Scottish National Antimicrobial Stewardship Programme. Int J Antimicrob Agents. 2011.

Drew. Antimicrobial stewardship programs: how to start and steer a successful program. J Manag Care Pharm. 2009.

Forskjellige faggruppers rolle

Pulcini et al. The impact of infectious disease specialists on antibiotic prescribing in hospitals. Clin Microbiol Infect. 2014

Wickens et al. The increasing role of pharmacists in antimicrobial stewardship in English hospitals. J Antimicrob Chemother. 2013.

Edwards et al. Covering more Territory to Fight Resistance: Considering Nurses’ Role in Antimicrobial Stewardship. J Infect Prev. 2011.

Global oversikt

Howard et al. An international cross-sectional survey of antimicrobial stewardship programmes in hospitals. J Antimicrob Chemother. 2014.

Trivedi et al. Identifying best practices across three countries: hospital antimicrobial stewardship in the United kingdom, France, and the United States. Clin Infect Dis. 2014.

Innhold

Nathwani  et al. Practical guide to antimicrobial stewardship in hospitals. BIOMERIEUX, 2013.

Charani et al. Antibiotic stewardship programmes–what’s missing? J Antimicrob Chemother. 2010.

Davey et al. Overview of strategies for overcoming the challenge of antimicrobial resistance. Expert Rev Clin Pharmacol. 2010.

Dellit et al. IDSA and SHEA guidelines for developing an institutional program to enhance antimicrobial stewardship. Clin Infect Dis. 2007.

Kunnskapsoppsummeringer

Davey et al. Interventions to improve antibiotic prescribing practices for hospital inpatients. Cochrane Database Syst Rev. 2013.

O’Brien et al. Educational outreach visits: effects on professional practice and health care outcomes. Cochrane Database Syst Rev. 2007.

Kvalitative studier

Broom et al. Cultures of resistance? A Bourdieusian analysis of doctors’ antibiotic prescribing. Soc Sci Med. 2014.

Charani et al. Understanding the Determinants of Antimicrobial Prescribing Within Hospitals: The Role of «Prescribing Etiquette». Clin Infect Dis. 2013.

Bjorkman et al. Perceptions among Swedish hospital physicians on prescribing of antibiotics and antibiotic resistance. Qual Saf Health Care. 2010.

Ledelse

Cosgrove et al. Guidance for the knowledge and skills required for antimicrobial stewardship leaders. Infect Control Hosp Epidemiol. 2014.

Nagel et al. Demonstrating the value of antimicrobial stewardship programs to hospital administrators. Clin Infect Dis. 2014.

Mikrobiologi

Kothari et al. Emerging technologies for rapid identification of bloodstream pathogens. Clin Infect Dis. 2014.

Pogue et al. Automated alerts coupled with antimicrobial stewardship intervention lead to decreases in length of stay in patients with gram-negative bacteremia. Infect Control Hosp Epidemiol. 2014.

Målinger

Septimus. Antimicrobial stewardship-qualitative and quantitative outcomes: the role of measurement. Current infectious disease reports. 2014.

McGregor et al. Optimizing research methods used for the evaluation of antimicrobial stewardship programs. Clin Infect Dis. 2014.

Khadem et al. Antimicrobial stewardship: a matter of process or outcome? Pharmacotherapy.  2012.

Pasientsikkerhet

Tamma et al. Antimicrobial stewardship: another focus for patient safety? Curr Opin Infect Dis. 2014.

 

Sist oppdatert 15. mars 2017